John wisely traded the sunny skies of Northern California for the “motivating” weather of the Boston area to study what he realized he was interested in his last year as an undergraduate: evolution. At the University of California, Berkeley, he performed research in the fields of enzymology and computational biology with the broad goal of understanding the structural determinants of enzyme function and how the evolution of these regions confers novel activity. When he joined the lab as an MCO graduate student via the MCB Department, John sought to combine biochemical and structural lines of investigation with genetics and developmental biology to study the molecular and evolutionary processes that underlie germ cell formation in divergent organisms. He was a joint PhD candidate with Prof. Andres Leschziner.
John was supported by a National Science Foundation Graduate Research Fellowship during his PhD candidacy.
John successfully defended his PhD thesis on April 16, 2015. Congratulations John! See pictures of the champagne toast here.
oskar Predates the Evolution of Germ Plasm in Insects. Ewen-Campen, B., Srouji, J.R., Schwager, E.E. and Extavour, C.G. Current Biology 22(23): 2278-2283 (2012). Read more in the Harvard Gazette and a Dispatch in Current Biology. Recommended by the Faculty of 1000.
Redefining stem cells and assembling germ plasm: key transitions in the evolution of the germ line. Srouji, J. R. and Extavour, C. Chapter 16, pp. 360-397 in Key Transitions in Animal Evolution, R. DeSalle and B. Schierwater, eds. CRC Press, Taylor & Francis Group; Science Publishers (2010)
Convergent evolution of novel protein function in shrew and lizard venom. Aminetzach, Y.T., Srouji, J.R., Kong, C.Y., and Hoekstra H.E. Current Biology. 19:1925-1931 (2009)
Recombinant expression of twelve evolutionarily diverse subfamily Ialpha aminotransferases. Muratore, K.E., Srouji, J.R., Chow, M.A., and Kirsch J.F. Protein Expression and Purification 57: 34-44 (2008)