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Isabel Baker

Graduate Student

      isabel_baker@g.harvard.edu
       

I am interested in the molecular and cellular mechanisms by which a single cell is transformed into a complex body with specialized compartments, and how this process has changed since multicellularity first emerged on Earth.

I began pursuing my interests in development as a student assistant in Diane Krause's lab at the Yale Stem Cell Center, where I worked with a graduate student to investigate the genetic determinants behind hematopoietic stem cell differentiation. Then, when I studied abroad in Tel Aviv as an undergrad at New York University, I conducted an independent research project in Uri Gophna's lab in the Tel Aviv University Department of Molecular Microbiology and Biotechnology, where I did a bioinformatic analysis on the role of personal ancestry in disease phenotype. When I arrived back in New York, I began doing research in Stephen Small's lab in the NYU Center for Developmental Genetics. Here, I employed computational and experimental approaches to develop a model of the genetic cis-regulatory network underpinning body organization in early fruit fly development.

In the Extavour Lab, I am a PhD student in the OEB graduate program. I'm interested in unveiling how segment generation and formation is achieved during cricket embryogenesis in the hopes of gaining a more thorough understanding of the exciting world of bilaterian body plan evolution.